By Ava T. Albrecht
Nearly 35 To forty Million american citizens Will take care of critical melancholy at some point soon of their Lives. even if You’Re A Newly clinically determined sufferer, Or a pal Or Relative, This booklet bargains support. the one quantity on hand to supply The Doctor’S And Patient’S View, a hundred Questions And solutions approximately melancholy offers Authoritative, useful solutions for your questions about healing procedures, recommendation On dealing with melancholy, resources Of help, and masses extra. Written by way of popular Psychiatrists, Drs. Ava T. Albrecht And Charles Herrick, With statement From either A sufferer And A friend, This booklet is a useful source For an individual dealing with The clinical, mental, And Emotional Turmoil Of This Debilitating situation
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Extra info for 100 Questions & Answers About Depression
22 • Depletion of serotonin (by other medications such as certain antihypertensives) can precipitate depression. • Patients who have successfully committed suicide by violent means have evidence for reduced serotonin levels in the central nervous system based on postmortem analyses. • Antidepressant medications increase the functional capacity of dopamine, serotonin, and norepinephrine to varying degrees in the brain. qxd 3/21/05 11:32 M Page 23 100 QUESTIONS & ANSWERS ABOUT DEPRESSION In depression, the biogenic amines are believed to be insufficient in quantity within the synaptic cleft, and thus, proper communication to the receiving neuron does not occur.
Some tests used in research protocols examine levels of certain stress hormones or look at brain functioning. These are research based only, however, and have no utility in clinical practice. Your doctor may order blood tests to check for any underlying conditions that may mimic depression such as low thyroid hormone. qxd 3/24/05 9:10 M Page 33 100 QUESTIONS & ANSWERS ABOUT DEPRESSION Diagnosis tests or electrocardiograms may be ordered for baseline purposes, depending on the medication that is to be prescribed, as some medications may have effects on certain organ systems in the body.
Other antidepressants, including the commonly used serotonin reuptake inhibitors, block the return or transport of serotonin or norepinephrine into the sending neuron so that more of the neurotransmitter remains in the cleft. Some studies have demonstrated evidence of similar brain changes in response to interventions other than medications, such as from psychotherapy, as well. It is important to keep in mind that it is not clear at present whether the “chemical imbalance” is the cause or result of depression as the two appear simultaneously.