An Atlas of Gastroenterology: A Guide to Diagnosis and by Cyrus R. Kapadia

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By Cyrus R. Kapadia

Going past mere analysis, An Atlas of Gastroenterology covers every little thing from swallowing problems to remedy of jaundiced and immuno-compromised sufferers. Tables, illustrations, and case histories placed the knowledge at your fingertips. prime specialists mix lucid textual content with broad illustrations to interpret the thoughts wanted for an organization grab of the subject. insurance contains swallowing problems, heartburn, dyspepsia, diarrhea, irritable bowel syndrome, colonic polyps and colon melanoma, pancreatitis, pancreatic melanoma, the jaundiced sufferer and the immuno-compromised sufferer. released largely for family members and first care physicians An Atlas of Gastroenterology describes all facets of the prognosis and therapy of gastrointestinal illness.

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Additional info for An Atlas of Gastroenterology: A Guide to Diagnosis and Differential Diagnosis

Sample text

Activity of spondylitis is not related to the activity of colitis and is not relieved after colectomy. Sacroileitis occurs in 10–15% of cases of ulcerative colitis if evidence is sought for by using radiology. When symptomatic, this results in low back pain. Most patients with sacroilitis are HLA-B27 negative. Muscle This is a polymyositis-like syndrome. Hepatic Sclerozing cholangitis ocurs in about 3% of patients with ulcerative colitis. 19 Differences between ulcerative colitis and Crohn’s disease Small intestine Esophagus or stomach Perianal disease abscess fistula fissure Layers of bowel involved Ulcerative colitis Crohn’s disease not involved never involved infrequent often involved rarely involved frequent – may be the initial presentation predominantly a mucosal disease all coats involved, disease often extending to serosa and to adjacent bowel loop present – often not seen on superficial biopsies small or large intestinal strictures frequent frequent enteroenteric enterocutaneous abdominal wall perinium enterovesicle enterouterine rectum frequently spared skip areas of normal mucosa often seen between diseased areas Granuloma absent Strictures Fistulae very rare to have colonic stricture absent Colonic disease Colonic disease rectum always involved involvement contiguous colitis who develop sclerozing cholangitis, 70% are HLA DR3 B8-positive.

Steady pain with toxic megacolon; (4) Fever – not uncommon during severe exacerbations (101–102 ºF, 38–39 °C); higher fevers rare and might suggest perforation following a megacolon; 42 (1) Fulminant colitis – the above symptoms unresponsive to medical treatment and requiring surgery; (2) Toxic megacolon Extraintestinal manifestations Skin Erythema nodosum is more commonly seen in children with Crohn’s disease. Pyoderma gangrenosum is more commonly seen in ulcerative colitis. ‘Metastatic’ Crohn’s disease – rare, nodular, necrotic, granulomatous skin lesions due to a vasculitis – is seen on the limbs and in women under the breasts or on the vulva.

Autoimmunity Associated autoimmune diseases are dermatitis herpetiformis, thyroiditis, alopecia, type 1 diabetes mellitus, autoimmune hepatitis and systemic lupus erythematosus. Patients diagnosed in infancy and treated with a gluten-free diet have shown associated autoimmune diseases in approximately 5%. Patients diagnosed in their twenties (including silent cases) have shown associated autoimmune diseases in 35%. It is concluded that continued presence of celiac disease results in the development of autoimmune disease in other organs.

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